The award is the equivalent of an MBE and is the highest award available to local volunteer groups.
The charity has about 40 volunteers ranging from those on the front line helping to deliver services or helping with outhouse activities in the community, to others supporting back office functions such as HR, accountancy and governance.
Executive director and trustee of Headway Guernsey Philippa Stahelin said the award recognised the work done by the volunteers who help each organisation.
She said: "From my point of view it's a recognition of the work the charity does but also a big, big "thank you" to the volunteers,'
"Like any organisation you can have your staff, but if you don't have volunteers you can't offer a service. It’s a real tribute to the value of our services and a major accolade to our volunteers.”
The awards will be presented by Lt-Governor Vice Admiral Sir Ian Corder at Government House during the Queen's birthday reception on 8 June. It will receive a certificate signed by Her Majesty The Queen and a domed glass crystal.