Psychiatric risk factors for traumatic brain injury

Close-up of a girl's eye

Abstract

Objective

To examine the risk of sustaining a traumatic brain injury (TBI) associated with prior psychiatric conditions beyond that of fixed demographic variables.

Design

Retrospective cohort study of non-referred community-dwelling male US veterans.

Methods

Two-hundred and seventy-one individuals who sustained a TBI with altered consciousness were compared with 630 controls without a history of head, selected from a larger sample of 3766.

Results

Hierarchical logistic regression analyses were used to model odds ratios and 95% confidence intervals for the unique association between pre-existing psychiatric disorders and the likelihood of incurring a TBI while adjusting for demographic characteristics and other known predictor variables. Mood (odds ratio 2.48, 95% confidence interval 1.23–5.01), anxiety (OR 1.64, 95% CI 1.01–2.68) and conduct disorders (OR 1.66, 95% CI 1.16–2.38) increased the risk of head injury.

Conclusions

The pre-existence of psychiatric illness, particularly depression, anxiety and conduct disorder, increased the future risk of incurring a TBI. The implementation of early identification and treatment of psychiatric conditions may potentially lower risk and reduce yearly incidence rates of TBI.

Reference: Vassallo, J.L., Proctor-Weber, Z., Lebowitz, B.K., Curtiss, G., & Vanderploeg, R.D. (2009). Psychiatric risk factors for traumatic brain injury. Brain Injury, 21(6), 567-573.